EPS15L1 Antibody - Cat. #: CSB-PA524180

SKU: CSB-PA524180

Size :50ul

Clone Number:

Aliases:EP15R_HUMAN antibody; epidermal growth factor receptor pathway substrate 15- ike 1 antibody; Epidermal growth factor receptor substrate 15 like 1 antibody; Epidermal growth factor receptor substrate 15-like 1 antibody; epidermal growth factor receptor substrate EPS15R antibody; Eps15 related protein antibody; Eps15-related protein antibody; EPS15L1 antibody; Eps15R antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBC2

Immunogen:Fusion protein of Human EPS15L1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EPS15L1

Research Areas:Signal transduction