EPOR (Ab-426) Antibody - Cat. #: CSB-PA826447

SKU: CSB-PA826447

Size :100ul

Clone Number:

Aliases:EPO R antibody; EPO Receptor antibody; EPO-R antibody; epor antibody; EPOR_HUMAN antibody; Erythropoietin receptor antibody; Erythropoietin receptor precursor antibody; MGC138358 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P19235

Immunogen:Synthesized peptide derived from Internal of Human Epo-R.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

Winkelmann J.C., Blood 76:24-30(1990) [PubMed: 2163695].
Jones S.S.,Blood 76:31-35(1990) [PubMed: 2163696].
Noguchi C.T., Blood 78:2548-2556(1991) [PubMed: 1668606].

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EPOR

Research Areas:Cardiovascular;Immunology;Signal transduction?Stem cells