EIF3K Antibody - Cat. #: CSB-PA693741

SKU: CSB-PA693741

Size :100ul

Clone Number:

Aliases:ARG134 antibody; eIF 3 p25 antibody; eIF 3 p28 antibody; eIF-3 p25 antibody; eIF-3 p28 antibody; EIF3-p28 antibody; eif3k antibody; EIF3K_HUMAN antibody; EIF3S12 antibody; Eukaryotic translation initiation factor 3 subunit 12 antibody; Eukaryotic translation initiation factor 3 subunit K antibody; HSPC029 antibody; M9 antibody; MSTP001 antibody; Muscle specific gene M9 protein antibody; Muscle-specific gene M9 protein antibody; PLAC 24 antibody; PLAC-24 antibody; PLAC24 antibody; PRO1474 antibody; PTD001 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBQ5

Immunogen:Synthesized peptide derived from internal of Human EIF3K.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. HAMAP-Rule MF_03010Mayeur G.L., Eur. J. Biochem. 270:4133-4139(2003).Nawa G., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.Ye M., Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EIF3K

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience