DNASE1 Antibody - Cat. #: CSB-PA065296

SKU: CSB-PA065296

Size :50ul

Clone Number:

Aliases:Deoxyribonuclease 1 antibody; Deoxyribonuclease I antibody; Deoxyribonuclease-1 antibody; Deoxyribonuclease1 antibody; DeoxyribonucleaseI antibody; DNAS1_HUMAN antibody; DNASE 1 antibody; DNase I antibody; DNase I lysosomal antibody; DNASE1 antibody; DNaseI antibody; DNL 1 antibody; DNL1 antibody; Dornase alfa antibody; DRNI antibody; FLJ38093 antibody; Human urine deoxyribonuclease I antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P24855

Immunogen:Fusion protein of Human DNASE1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DNASE1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism