DNA pol Epsilon A Polyclonal Antibody

SKU: BT-AP02661

Size:100μL

Background:POLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:POLE

applications:IHC-p, ELISA

Reactivity:Human, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DNA pol epsilon A Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):261518

UniProt accession:Human: Q07864; Mouse: Q9WVF7

Synonyms:POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A

GeneID:Human: 5426