Dio3 Antibody, Biotin conjugated - Cat. #: CSB-PA344617LD01RA

SKU: CSB-PA344617LD01RA

Size :50ug

Clone Number:

Aliases:Dio3 antibody; Itdi3 antibody; Txdi3 antibody; Thyroxine 5-deiodinase antibody; EC 1.21.99.3 antibody; 5DIII antibody; DIOIII antibody; Type 3 DI antibody; Type III iodothyronine deiodinase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rattus norvegicus (Rat)

UniProt ID:P49897

Immunogen:Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA)

Raised in:Rabbit

Species Reactivity:Rat

Tested Applications:ELISA

Background:Responsible for the deiodination of T4 (3,5,3\\\',5\\\'-tetraiodothyronine) into RT3 (3,3\\\',5\\\'-triiodothyronine) and of T3 (3,5,3\\\'-triiodothyronine) into T2 (3,3\\\'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Dio3

Research Areas:Neuroscience; Cancer; Metabolism; Signal transduction