DCK Polyclonal Antibody

SKU: E-AB-14732

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DCK

Target Synonym: dCK;DCK protein;DCK;Deoxycytidine kinase;Deoxynucleoside kinase;EC 2.7.1;EC 2.7.1.74;MGC117410;MGC138632;OTTHUMP00000219118;OTTHUMP00000219119

Research Areas: Cancer;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P27707

Accession:

Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human DCK

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1:1000

Calculated MW: 31kDa

ObservedMW: