Cytotoxin 4 Antibody, HRP conjugated - Cat. #: CSB-PA355645LB01NFG

SKU: CSB-PA355645LB01NFG

Size :50ug

Clone Number:

Aliases:antibody; Cytotoxin 4 antibody; CTX-4M antibody; CTX4 antibody; Cardiotoxin A4 antibody; CTX A4 antibody; Cardiotoxin analog IV antibody; CTX IV antibody

Product Type:Polyclonal Antibody

Immunogen Species:Naja atra (Chinese cobra)

UniProt ID:P01443

Immunogen:Recombinant Naja atra Cytotoxin 4 protein (22-81AA)

Raised in:Rabbit

Species Reactivity:Naja atra

Tested Applications:ELISA

Background:Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:

Research Areas:Others