Cytokeratin (Pan) Monoclonal Antibody

SKU: BT-MCA4209

Size:100μL

Background:Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors.

Research_area:Others

Target_protein:Cytokeratin (Pan)

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:7H8C4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:Cytokeratin (Pan)

Immunogen:Purified recombinant fragment of CK5 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P13647

Synonyms:K5, DDD, EBS2, KRT5A, KRT5

GeneID:3852