cTnI Monoclonal Antibody

SKU: BT-MCA2301

Size:100μL

Background:cTnI has an apparent molecular weight of 22.5 kDa. cTnI is a candidate marker with acceptable sensitivity and specificity for AMI and other cardiac diseases. Troponin, a molecule that binds to the thin filament (actin) of striated muscle fibers, acts with intracellular calcium to control the interaction of the thin filament with the thick filament (myosin), thus regulating muscle contraction. Troponin I prevents muscle contraction in the absence of calcium, which has two skeletal muscle isoforms with considerable amino acid sequence homology. cTnI contains an additional N-terminal sequence and is highly specific for myocardium.

Research_area:Others

Target_protein:cTnI

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:3A10A12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:cTnI

Immunogen:Purified recombinant fragment of cTnI expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P19429

Synonyms:CMH7, RCM1, cTnI, CMD2A, TNNC1

GeneID:7137