Crystallin-alpha C Polyclonal Antibody

SKU: E-AB-10378

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HSPB8

Target Synonym: Alpha crystallin C chain;Alpha-crystallin C chain;Charcot Marie Tooth disease axonal type 2L;Charcot Marie Tooth disease spinal;CMT2L;CRYAC;DHMN 2;DHMN2;E2 induced gene 1 protein;E2-induced gene 1 protein;E2IG1;H11;Heat shock 22kDa protein 8;Heat shock 27kDa protein 8;Heat shock protein 22;Heat shock protein beta 8;Heat shock protein beta-8;Hereditary motor neuropathy distal;HMN 2;HMN2;HMN2A;HSB8;HSPB 8;Hspb8;HSPB8;OTTHUMP00000239768;Protein kinase H11;Small stress protein like protein HSP22;Small stress protein-like protein HSP22;Spinal muscular atrophy distal adult autosomal dominant

Research Areas: Cancer;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UJY1

Accession:

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human HSPB8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: