CREB-1(Phospho Ser133) Polyclonal Antibody

SKU: BT-AP00472

Size:100μL

Background:This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Research_area:Epigenetics and nuclear signaling; Immunology

Target_protein:CREB1

applications:IF, ICC, WB, IHC-p, IP, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Cyclic AMP-responsive element-binding protein 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):36688

UniProt accession:Human: P16220; Mouse: Q01147; Rat: P15337

Synonyms:Cyclic AMP-responsive element-binding protein 1; CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1

GeneID:Human: 1385; Mouse: 12912; Rat: 81646