CPEB1 Antibody, Biotin conjugated - Cat. #: CSB-PA861184LD01HU

SKU: CSB-PA861184LD01HU

Size :50ug

Clone Number:

Aliases:CEBP antibody; CPE binding protein 1 antibody; CPE BP1 antibody; CPE-binding protein 1 antibody; CPE-BP1 antibody; CPEB 1 antibody; CPEB antibody; CPEB-1 antibody; CPEB1 antibody; CPEB1 protein antibody; CPEB1_HUMAN antibody; Cytoplasmic polyadenylation binding protein 1 antibody; Cytoplasmic polyadenylation element binding protein antibody; Cytoplasmic polyadenylation element binding protein 1 antibody; Cytoplasmic polyadenylation element-binding protein 1 antibody; FLJ13203 antibody; h CEBP antibody; h-CEBP antibody; hCPEB 1 antibody; hCPEB-1 antibody; MGC34136 antibody; MGC60106 antibody; mKIAA0940 antibody; MKIAA0940 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BZB8

Immunogen:Recombinant Human Cytoplasmic polyadenylation element-binding protein 1 protein (1-486AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\'-UUUUUAU-3\') within the mRNA 3\'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CPEB1

Research Areas:Epigenetics and Nuclear Signaling