COX7A2L Polyclonal Antibody

SKU: E-AB-52144

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: COX7A2L

Target Synonym: COX7a related protein;COX7a-related protein;COX7A2L;COX7AR;COX7R;COX7RP;Cytochrome c oxidase subunit 7A-related protein;cytochrome c oxidase subunit 7A-related protein; mitochondrial;Cytochrome c oxidase subunit 7A2 like;cytochrome c oxidase subunit VII-related protein;cytochrome c oxidase subunit VIIa polypeptide 2 like;Cytochrome c oxidase subunit VIIa related protein; mitochondrial;Cytochrome c oxidase subunit VIIa-related protein;EB1;Estrogen receptor binding CpG island;mitochondrial;SIG81

Research Areas: Cancer;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O14548

Accession:

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.

Concentration: 2.5 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:30-1:150

Calculated MW:

ObservedMW: