COX11 Antibody - Cat. #: CSB-PA277061

SKU: CSB-PA277061

Size :50ul

Clone Number:

Aliases:COX11 antibody; COX11 homolog antibody; COX11 homolog; cytochrome c oxidase assembly protein (yeast) antibody; COX11_HUMAN antibody; COX11P antibody; Cytochrome c oxidase assembly protein COX11 antibody; Cytochrome c oxidase assembly protein COX11; mitochondrial antibody; Cytochrome c oxidase subunit 11 antibody; mitochondrial antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6N1

Immunogen:Fusion protein of Human COX11

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100

Background:Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:COX11

Research Areas:Others