Cleaved-Aggrecan (D369) Polyclonal Antibody

SKU: BT-AP01878

Size:100μL

Background:ACAN is a member of the aggrecan/versican proteoglycan family. Aggrecan core protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

Research_area:Others

Target_protein:ACAN

applications:WB, IHC-p, ELISA

Reactivity:Human, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Cleaved-Aggrecan (D369) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):250193

UniProt accession:Human: P16112; Mouse: Q61282; Rat: P07897

Synonyms:ACAN; AGC1; CSPG1; MSK16; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1

GeneID:Human: 176; Rat: 58968