CHOP Polyclonal Antibody

SKU: E-AB-70087

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CHOP

Target Synonym:C/EBP homologous protein;C/EBP Homology Protein;C/EBP zeta;C/EBP-homologous protein 10;C/EBP-homologous protein;CCAAT/enhancer binding protein homologous protein;CEBPZ;CHOP 10;CHOP;CHOP-10;CHOP10;DDIT 3;DDIT-3;Ddit3;DDIT3;DNA Damage Inducible Transcript 3;DNA damage-inducible transcript 3 protein;GADD 153;GADD153;Growth Arrest and DNA Damage Inducible Protein 153;Growth arrest and DNA damage inducible protein GADD153;Growth arrest and DNA damage-inducible protein GADD153;MGC4154

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Developmental Biology;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P35638,P35639,Q62857

Accession:

Background:CHOP,also known as GADD153 or DDIT3,is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins,CHOP is significantly induced by ER stress,deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.

Concentration:1 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse CHOP

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:100-500

Calculated MW:

ObservedMW: