CDKN1C Monoclonal Antibody

SKU: BT-MCA3411

Size:100μL

Background:The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.

Research_area:Cell Biology

Target_protein:CDKN1C

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:3E3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CDKN1C

Immunogen:Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):57kDa

UniProt accession:P49918

Synonyms:BWS, WBS, p57, BWCR, KIP2, CDKN1C

GeneID:1028