CDK2 Monoclonal Antibody

SKU: BT-MCA3931

Size:100μL

Background:The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Research_area:Cell Biology

Target_protein:CDK2

applications:WB, IHC, ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:1A6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CDK2

Immunogen:Purified recombinant fragment of human CDK2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):33.9kDa

UniProt accession:P24941

Synonyms:p33

GeneID:1017