CDK1 Polyclonal Antibody

SKU: E-AB-70286

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CDK1

Target Synonym:Cdc 2;Cdc2;CDC28A;CDK 1;CDK1;CDK1;CDKN1;CELL CYCLE CONTROLLER CDC2;Cell division control protein 2;Cell division control protein 2 homolog;Cell division cycle 2 G1 to S and G2 to M;Cell division protein kinase 1;Cell Divsion Cycle 2 Protein;Cyclin Dependent Kinase 1;Cyclin-dependent kinase 1;DKFZp686L20222;MGC111195;p34 Cdk1;p34 protein kinase;P34CDC2

Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P06493,P11440,P39951

Accession:

Background:CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2.

Concentration:2.5 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to mouse CDK1

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:34kDa

ObservedMW:34kDa