CD97 Monoclonal Antibody

SKU: BT-MCA2852

Size:100μL

Background:This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Research_area:Neuroscience

Target_protein:CD97

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6D7E6

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:CD97

Immunogen:Purified recombinant fragment of human CD97 (AA: extra 419-552) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):91.8kDa

UniProt accession:P48960

Synonyms:ADGRE5, TM7LN1

GeneID:976