CD59 antibody , Cat. # FNab01489

SKU: FNab01489

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Immunogen:CD59 molecule, complement regulatory protein

Synonyms:MIC11, MIN1, MIN2, MIN3, MSK21

Observed MW:18-20 kDa

Uniprot ID:P13987

Reactivity:Human

Tested Application:ELISA, WB, IHC, FC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:966

Research Area:Stem Cells, Immunology, Signal Transduction