CD49E Monoclonal Antibody

SKU: BT-MCA3960

Size:100μL

Background:The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Research_area:Others

Target_protein:CD49E

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:8D1G12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD49E

Immunogen:Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):114.5kDa

UniProt accession:P08648

Synonyms:ITGA5, FNRA, VLA-5, VLA5A

GeneID:3678