CD41/Integrin α/2b Mouse mAb

SKU: EM1106

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):

Human_gene_id:3674

Human_swiss_prot_no:P08514

Subcellular_location:Membrane

Other_name:BDPLT2,CD41 antigen, CD41a, gp2b, ITGA2B, platelet fibrinogen receptor alpha

Background:ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation.