Cd2ap antibody , Cat. # FNab01455

SKU: FNab01455

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.

Immunogen:CD2-associated protein

Synonyms:

Observed MW:70 kDa

Uniprot ID:Q9Y5K6

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IF, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

Gene ID:23607

Research Area:Signal Transduction