CD2AP Antibody - Cat. #: CSB-PA004914LA01HU

SKU: CSB-PA004914LA01HU

Size :50ug

Clone Number:

Aliases:Adapter protein CMS antibody; AL024079 antibody; C78928 antibody; Cas ligand with multiple SH3 domains antibody; CD2 associated protein antibody; CD2-associated protein antibody; CD2AP antibody; CD2AP_HUMAN antibody; CMS antibody; Mesenchyme to epithelium transition protein with SH3 domains 1 antibody; METS 1 antibody; Mets1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y5K6

Immunogen:Recombinant Human CD2-associated protein (333-426AA)

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background:Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CD2AP

Research Areas:Signal transduction