CD258 Monoclonal Antibody

SKU: BT-MCA4772

Size:100μL

Background:The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Research_area:Others

Target_protein:CD258

applications:ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:1F4A5

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:CD258

Immunogen:Purified recombinant fragment of human CD258 (AA: extra 59-240) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):26.3kDa

UniProt accession:O43557

Synonyms:TNFSF14, LTg, HVEML, LIGHT

GeneID:8740