CD177 Monoclonal Antibody

SKU: BT-MCA3380

Size:100μL

Background:This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Research_area:Immunology

Target_protein:CD177

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2F2C5

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:CD177

Immunogen:Purified recombinant fragment of human CD177 (AA: extra 22-161) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):46.4kDa

UniProt accession:Q8N6Q3

Synonyms:NB1, PRV1, HNA2A, PRV-1, HNA-2a, NB1 GP

GeneID:57126