Cd163 Antibody, HRP conjugated - Cat. #: CSB-PA650452LB01MO

SKU: CSB-PA650452LB01MO

Size :50ug

Clone Number:

Aliases:Cd163 antibody; M130Scavenger receptor cysteine-rich type 1 protein M130 antibody; CD antigen CD163) [Cleaved into: Soluble CD163 antibody; sCD163)] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:Q2VLH6

Immunogen:Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Cd163

Research Areas:Cardiovascular; Immunology