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GeneBio Systems

CD16 Monoclonal Antibody

CD16 Monoclonal Antibody

SKU:E-AB-22048

Regular price €492,95 EUR
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: CD16

Target Synonym: CD 16;CD 16a;CD16;CD16a;CD16B;Fc fragment of IgG;Fc fragment of IgG low affinity IIIa receptor (CD16);Fc gamma R3;Fc gamma receptor III 2 (CD 16);Fc gamma receptor III A;Fc of IgG;Fc-gamma receptor III2 (CD 16);Fc-gamma RIII;Fc-gamma RIII-alpha;Fc-gamma RIIIa;FCG 3;FCG3;FCG3A;FC gamma RIIIA;FCGR 3;FCGR 3A;FCGR3;FCGR3A;FCGR3A protein;FCGRIII;FCGRIII-2;FcR 10;FcR-10;FcR10;FcRIII;FcRIIIa;IGFR 3;IGFR3;IgG Fc receptor III 1;IgG Fc receptor III 2;IgG Fc receptor III-2;IMD20;immunoglobulin G Fc receptor III;immunoglobulin G Fc receptor III-2;Low affinity IIIa receptor;Low affinity immunoglobulin gamma Fc region receptor III A;neutrophil-specific antigen NA

Research Areas: Cancer;Immunology;Stem Cells

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human

Application: WB;IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:2B1

UNIProt ID: P08637,O75015

Accession:

Background: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Dilution: WB 1:500-1:2000;IHC 1:50-300

Calculated MW: 28kDa

ObservedMW: 45kDa

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