CD155 rabbit pAb

SKU: ES4358

Size: 100μL

Source:Rabbit

Applications:WB IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human PVR. AA range:81-130

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):70kD

Human_gene_id:5817

Human_swiss_prot_no:P15151

Subcellular_location:[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.

Other_name:PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155

Background:The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],