CAPN2 Antibody - Cat. #: CSB-RA899086A0HU

SKU: CSB-RA899086A0HU

Size :50ul

Clone Number:17E9

Aliases:Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain), CAPN2, CANPL2

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P17655

Immunogen:A synthesized peptide derived from human CAPN2

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000

Background:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity). {ECO:0000250|UniProtKB:O08529, ECO:0000269|PubMed:17650508}.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CAPN2

Research Areas:Cancer; Cell biology; Metabolism; Signal transduction