Canine DNA repair protein RAD51 homolog 1,RAD51 ELISA KIT

SKU: E0066Ca

Size:96 Tests-1 Kit

Background:Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair. {ECO:0000250|UniProtKB:Q06609}.

Research_area:

Applications:ELISA

Target_protein:RAD51

Reactivity:Canine

Assay type:Sandwich

Sensitivity:0.051ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:DNA repair protein RAD51 homolog 1

Species:Canine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8MKI8

MASS(Da):36955

GeneID:403568

Synonyms:RAD51

Gene names:RAD51

Standard solution:32ng/ml