C8 α rabbit pAb

SKU: ES8864

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000, ELISA 1:10000-20000

Immunogen:Synthesized peptide derived from human C8 α. at AA range: 201-250

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):60kD

Human_gene_id:731

Human_swiss_prot_no:P07357

Subcellular_location:Secreted. Cell membrane; Multi-pass membrane protein. Secreted as soluble protein. Inserts into the cell membrane of target cells.

Other_name:Complement component C8 alpha chain (Complement component 8 subunit alpha)

Background:C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008],