Bovine Myeloid Differentiation Primary Response Protein Myd88, MYD88 ELISA Kit

SKU: E2236Bo

Size:96 Tests-1 Kit

Background:Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (PubMed: 17936907, PubMed: 18760477). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:MYD88

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:8.12ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Myeloid Differentiation Primary Response Protein Myd88

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q599T9

MASS(Da):33,709

GeneID:444881

Synonyms:MYD 88;MYD88;Myeloid differentiation primary response protein MyD88

Gene names:MYD88

Standard solution:3200ng/L