Bovine Integrin Alpha-L, ITGAL ELISA Kit

SKU: E0324Bo

Size:96 Tests-1 Kit

Background:Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating the role in lymphopoiesis. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ITGAL

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:5.26ng/L

Detection range:10-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Integrin Alpha-L

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P61625

MASS(Da):128,726

GeneID:281874

Synonyms:CD antigen CD11a;CD11 antigen-like family member A;Integrin alpha-L;ITGAL;Leukocyte adhesion glycoprotein LFA-1 alpha chain;Leukocyte function-associated molecule 1 alpha chain;LFA-1A

Gene names:ITGAL

Standard solution:3200ng/L