Bovine Fructose-1,6-bisphosphatase 1,FBP1 ELISA KIT

SKU: E0137Bo

Size:96Tests

Background:Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. {ECO:0000250|UniProtKB:P09467}.

Research_area:

Applications:ELISA

Target_protein:FBP1

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.6ng/ml

Detection range:1.25-80ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fructose-1,6-bisphosphatase 1

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q3SZB7

MASS(Da):36728

GeneID:513483

Synonyms:FBP1

Gene names:FBP1

Standard solution:160ng/ml