Bovine DNA repair protein RAD51 homolog 1,RAD51 ELISA KIT

SKU: E0084Bo

Size:96Tests

Background:Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair. {ECO:0000250|UniProtKB:Q06609}.

Research_area:

Applications:ELISA

Target_protein:RAD51

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.095ng/ml

Detection range:0.2-70ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:DNA repair protein RAD51 homolog 1

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q2KJ94

MASS(Da):36982

GeneID:514749

Synonyms:RAD51

Gene names:RAD51

Standard solution:80ng/ml