Bovine CXC-chemokine receptor 4,CXCR4 ELISA KIT

SKU: E0181Bo

Size:96 Tests-1 Kit

Background:Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival (By similarity). {ECO:0000250|UniProtKB:P61073, ECO:0000250|UniProtKB:P70658}.

Research_area:

Applications:ELISA

Target_protein:CXCR4

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.31ng/ml

Detection range:0.5-300ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:CXC-chemokine receptor 4

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P25930

MASS(Da):39939

GeneID:281736

Synonyms:CXCR4

Gene names:CXCR4

Standard solution:320ng/ml