Bovine ATP-sensitive inward rectifier potassium channel 12,KCNJ12 ELISA KIT

SKU: E0171Bo

Size:96Tests

Background:Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:KCNJ12

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:28.03ng/L

Detection range:50-3200ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:ATP-sensitive inward rectifier potassium channel 12

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q4TZY1

MASS(Da):48442

GeneID:538479

Synonyms:KCNJ12

Gene names:KCNJ12

Standard solution:6400ng/L