Bovine 10 kDa heat shock protein, mitochondrial,HSP10 ELISA KIT

SKU: E2085Bo

Size:96 Tests-1 Kit

Background:Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein. {ECO:0000250|UniProtKB:P61604}.

Research_area:

Applications:ELISA

Target_protein:HSPE1

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.036ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Heat Shock Protein 10

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P61603

MASS(Da):10932

GeneID:281833

Synonyms:HSPE1

Gene names:HSPE1

Standard solution:48ng/ml