Biotin Anti-Human CD32 Antibody[IV-3]

SKU: GBS-F1075B

Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD32

Target Synonym:IGFR2;CD32;CDw32;FCG2;FCGR2B;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b

Research Areas:Immunology;Innate Immunity

Conjugation:Biotin

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Mouse IgG2b, κ

Clonality:Monoclonal

Clone NO.:IV-3

UNIProt ID:P31994

Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Concentration:0.5 mg/mL

Control catalog number:E-AB-F09813B

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:2212