BEST2 rabbit pAb

SKU: ES20818

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Mouse;Rat

Dilution:WB: 1:500-1000 IHC: 1:200-500

Immunogen:Synthetic Peptide of BEST2

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:

Observed_band(KD):50kD

Human_gene_id:54831

Human_swiss_prot_no:Q8NFU1

Subcellular_location:Cell membrane; Multi-pass membrane protein.

Other_name:Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1

Background:This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008],