BEST1 Antibody - Cat. #: CSB-PA269030

SKU: CSB-PA269030

Size :50ul

Clone Number:

Aliases:ARB antibody; BEST 1 antibody; BEST antibody; Best disease antibody; Best macular dystrophy antibody; BEST1 antibody; BEST1_HUMAN antibody; Best1V1Delta2 antibody; Bestrophin 1 antibody; Bestrophin-1 antibody; Bestrophin1 antibody; BMD antibody; mBest1 antibody; RP50 antibody; TU15B antibody; Vitelliform macular dystrophy 2 antibody; Vitelliform macular dystrophy antibody; Vitelliform macular dystrophy protein 2 antibody; VMD 2 antibody; VMD2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O76090

Immunogen:Synthetic peptide of Human BEST1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BEST1

Research Areas:Neuroscience