BAP1 Antibody - Cat. #: CSB-PA985124

SKU: CSB-PA985124

Size :50ul

Clone Number:

Aliases:BAP 1 antibody; Bap1 antibody; BAP1_HUMAN antibody; BRCA 1 associated protein 1 antibody; BRCA1 associated protein 1 antibody; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody; BRCA1-associated protein 1 antibody; Cerebral protein 13 antibody; Cerebral protein 6 antibody; DKFZp686N04275 antibody; FLJ35406 antibody; FLJ37180 antibody; HUCEP 13 antibody; Hucep 6 antibody; HUCEP13 antibody; Hucep6 antibody; KIAA0272 antibody; TPDS antibody; Ubiquitin carboxy terminal hydrolase antibody; Ubiquitin carboxyl terminal hydrolase BAP 1 antibody; Ubiquitin carboxyl terminal hydrolase BAP1 antibody; Ubiquitin carboxyl-terminal hydrolase BAP1 antibody; UCHL2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92560

Immunogen:Fusion protein of Human BAP1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BAP1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology