BAIAP2 Antibody - Cat. #: CSB-PA585175

SKU: CSB-PA585175

Size :50ul

Clone Number:

Aliases:BAI-associated protein 2 antibody; BAI1 associated protein 2 antibody; BAI1-associated protein 2 antibody; BAIAP 2 antibody; Baiap2 antibody; BAIP2_HUMAN antibody; BAP2 antibody; Brain-specific angiogenesis inhibitor 1-associated protein 2 antibody; Fas ligand-associated factor 3 antibody; FLAF3 antibody; Insulin receptor substrate p53 antibody; Insulin receptor substrate p53/p58 antibody; Insulin receptor substrate protein of 53 kDa antibody; IRS-58 antibody; IRSp53 antibody; IRSp53/58 antibody; Protein BAP2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UQB8

Immunogen:Fusion protein of Human BAIAP2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200

Background:The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BAIAP2

Research Areas:Neuroscience