BAD Monoclonal Antibody

SKU: BT-MCA3850

Size:100μL

Background:The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Research_area:Cell Biology

Target_protein:BAD

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1G5B3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:BAD

Immunogen:Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):18.4kDa

UniProt accession:Q92934

Synonyms:BBC2, BCL2L8

GeneID:572