AZU1 Antibody - Cat. #: CSB-PA002485ESR1HU

SKU: CSB-PA002485ESR1HU

Size :50ul

Clone Number:

Aliases:Azu 1 antibody; AZU1 antibody; Azurocidin antibody; CAP37 antibody; CAP7_HUMAN antibody; Cationic antimicrobial protein 37 antibody; Cationic antimicrobial protein CAP37 antibody; HBP antibody; Heparin binding protein antibody; Heparin-binding protein antibody; HUMAZUR antibody; Neutrophil azurocidin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20160

Immunogen:Recombinant Human Azurocidin protein (27-251AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AZU1

Research Areas:Cardiovascular; Immunology; Microbiology