AXL Monoclonal Antibody

SKU: BT-MCA3979

Size:100μL

Background:AXL: AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research_area:Cell Biology

Target_protein:AXL

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:1B3A2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:AXL

Immunogen:Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P30530

Synonyms:UFO, JTK11

GeneID:558