ATP7B antibody , Cat. # FNab09849

SKU: FNab09849

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Immunogen:ATP7B

Synonyms:PWD, WC1, WD, WND

Observed MW:150 kDa

Uniprot ID:P35670

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500 - 1:2000; IF: 1:50 - 1:200

Gene ID:540

Research Area:Signal Transduction, Metabolism